Tsyr-Yan Yu(余慈顏)
Title: Associate Research Fellow
Telephone: 886-2-2366-8210
E-Mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Office: Room 231, Institute of Atomic and Molecular Sciences, Academia Sinica
Lab: Room 221, Institute of Atomic and Molecular Sciences, Academia Sinica
Lab homepage: http://labs.iams.sinica.edu.tw/project/dharma
Education:
2008 | Ph.D., Chemistry, Washington University in St. Louis, USA
2000 | M.S., Chemistry, National Taiwan University, Taipei, Taiwan
1998 | B.S., Chemistry, National Taiwan University, Taipei, Taiwan
Experience:
Nov. 2013 - present | Assistant Research Fellow, Institute of Atomic and Molecular Sciences, Academia Sinica, Taiwan
Jan. 2009 - Oct. 2013 | Postdoctoral Research Associate, Harvard University, USA
Aug. 2008 - Oct. 2008 | Postdoctoral Research Associate, Washington University in St. Louis, USA
Honors & Awards:
2017 | Young Scholar Creativity and innovation Award, Foundation For The Advancement of Outstanding Scholarship.
2009 | Fellowship, Postdoctoral Research Abroad Program, National Science Council, Taiwan.
2008 | Student Award, The 49th Experimental Nuclear Magnetic Resonance Conference
2004 | TA Teaching Award, Washington University in St. Louis
Research Highlight:
Membrane Protein Research
NMR spectroscopy
Molecular Basis of Familial Amyloid Polyneuropathy
Representative publications:
- Vivien Yeh, Tsung-Yen Lee, Chung-Wen Chen, Pai-Chia Kuo, Jessie Shiue, Li-Kang Chu,* and Tsyr-Yan Yu*, Highly Efficient Transfer of 7TM Membrane Protein from Native Membrane to Covalently Circularized Nanodisc, Scientific Reports, DOI: 10.1038/s41598-018-31925-1 (2018).
- Orion Shih, Yi-Qi Yeh, Kuei-Fen Liao, Chun-Jen Su, Pei-Hao Wu, Richard K. Heenan, Tsyr-Yan Yu*, and U-Ser Jeng*, Membrane Charging and Swelling upon Calcium Adsorption as Revealed by Phospholipid Nanodiscs, Journal of Physical Chemistry Letters, 9, 4287 (2018).
- Yustina Yusuf, Julien Massiot, Yu-Ting Chang, Pei-Hao Wu, Vivien Yeh, Pai-Chia Kuo, Jessie Shiue*, Tsyr-Yan Yu*, Optimization of the production of covalently circularized nanodiscs and their characterization in physiological conditions, Langmuir, 34, 3525 (2018).
- Vivien Yeh, Yin Hsin, Tsung-Yen Lee, Jerry Chun Chung Chan, Tsyr-Yan Yu*, and Li-Kang Chu*, Lipids Influence the Proton Pump Activity of Photosynthetic Protein Embedded in Nanodiscs, RCS Advances, 6, 88300-88305 (2016).
- Tsung-Yen Lee, Vivien Yeh, Julia Chuang, Jerry Chun Chung Chan, Li-Kang Chu, Tsyr-Yan Yu*, Tuning the Photocycle Kinetics of Bacteriorhodopsin in Lipid Nanodiscs, Biophys. J., 109(9), 1899-1906 (2015).